SOLICITATIONS
Solicitations issued by the SMA Project in the form of Requests for Proposals (RFPs) or Requests for Quotes (RFQs) are targeted toward specific needs or capabilities for carrying out the program plan developed by the program’s Steering Committee.
CURRENT SOLICITATIONS: Currently, there are no open RFPs or RFQs. Individuals who sign up for the SMA Project ListServ will automatically be notified within 24 hours of the release of any new SMA Project solicitation.
Back to top
PRIOR SOLICITATIONS: The following Solicitations have been issued by the SMA Project:
- Preclinical Studies of Small Molecules with Therapeutic Potential for Spinal Muscular Atrophy (closed October 5, 2007)
- In Vitro Profiling Services for Pharmacologic, ADME, and Toxicologic Activities of Small Molecules (closed April 5, 2007)
- Development of an Automated SMN Gem Assay Suitable for Medium-Throughput Screening (posted August 1, 2006)
- A Centralized Information Technology (IT) System for the SMA Project (closed April 8, 2005)
- An In Vitro Biological Assay Facility for Screening Compounds in Cellular Models of Spinal Muscular Atrophy (closed December 21, 2004)
- Facilities for Chemical Optimization and Synthesis of Small Molecules for the SMA Project (closed September 14, 2004)
- A Mouse Testing Facility for Screening of Small Molecule Therapeutics for Spinal Muscular Atrophy (closed September 8, 2004)
- A Protein Detection Kit for Quantifying Survival Motor Neuron (SMN) Protein (closed April 13, 2004)
- Motor Neuron Cellular Models of Spinal Muscular Atrophy (SMA) (closed April 9, 2004)
- Inducible Mouse Model of Spinal Muscular Atrophy (closed December 23, 2003)
Back to top
SMA PROJECT AWARDS
SMA Project Awards are made to successful Offerors in the form of subcontracts to SAIC. Subcontracts awarded under this program will be in compliance with the provisions and spirit of the Principles and Guidelines for Recipients of NIH Grants and Contracts on Obtaining and Disseminating Biomedical Research Resources (64 FR 72090, December 1999), and the Bayh-Dole Act (35 USC 200, et seq.).
As of April 1, 2008, the following subcontracts have been awarded by the SMA Project:
Preclinical Studies of Small Molecules with Therapeutic Potential for Spinal Muscular Atrophy
Bayer CropScience, LP
Principal Investigator – Devendra Dandekar
Period of Performance – February 28, 2008 to September 25, 2009
Research Triangle Institute, International (RTI, International)
Principal Investigator – Jim Mathews
Period of Performance – January 4, 2008 to September 25, 2009
In Vitro Profiling Services for Pharmacologic, ADME, and Toxicologic Activities of Small Molecules
Cerep
Principal Investigator – Sam Paliwal
Period of Performance – July 20, 2007 to September 25, 2009
MDS Pharma Services
Principal Investigator – Jamie Baumgartner
Period of Performance – July 9, 2007 to September 25, 2009
SMN Reporter Assay Screening to Support the SMA Project
Southern Research Institute
Principal Investigator – Joe Maddry
Period of Performance – November 3, 2006 to September 25, 2009
Development of an Automated SMN Gem Assay Suitable for Medium-Throughput Screening
Cellumen
Principal Investigator – Kate Johnston
Period of Performance – October 27, 2006 to September 25, 2009
Facilities for Chemical Optimization and Synthesis of Small Molecules for the SMA Project
Albany Molecular Research, Inc. (AMRI)
Principal Investigator – Keith Barnes
Period of Performance – June 8, 2005 to September 25, 2009
Executive Summary
In Vivo Pharmacology and Toxicology Support for SMA Project
Research Triangle Institute, International (RTI, International)
Principal Investigator – Jim Mathews
Period of Performance – March 10, 2006 to September 25, 2009
Executive Summary
In Vitro Biological Assay Support for SMA Project
CombinatoRx Inc. (CRXX)
Principal Investigator – Jane Staunton
Period of Performance – August 9, 2005 to September 28, 2007
Executive Summary
In Vivo Efficacy Testing to Support the SMA Project
Psychogenics Inc. (PGI)
Principal Investigator – Emer Leahy
Period of Performance – September 15, 2005 to September 25, 2009
Executive Summary
Centralized Information Technology (IT) System for Data Collection and Storage
CambridgeSoft, Inc.
Point of Contact – Louis Culot
Period of Performance – May 15, 2005 to September 25, 2009
Executive Summary
A 96-well Sandwich ELISA for SMN
Robert Jones and Agnes Hunt (RJAH) Orthopedic Hospital
Principal Investigator – Glenn Morris
Period of Performance – October 21, 2005 to February 28, 2007
Executive Summary
A Cell Culture Model for SMA Using Embryonic Stem Cell-Derived Motoneurons
Johns Hopkins University
Principal Investigator – Douglas Kerr
Period of Performance – November 9, 2004 to January 8, 2006
Executive Summary
A Human Embryonic Stem Cell-Derived Motor Neuron System for SMA Drug Development
The University of Georgia Research Foundation, Inc.
Principal Investigator – Steven Stice
Period of Performance – November 9, 2004 to November 8, 2005
Executive Summary
Inducible SMN Mouse Model
Children's Research Institute
Principal Investigator- Dawn Chandler
Period of Performance- October 17, 2005 to September 30, 2006
Executive Summary
Disruption of the Mouse SMN Locus with a Lox P Flanked tTA Flanked Expression Cassette to Allow Inducible Expression of SMN
The Ohio State University
Principal Investigator – Arthur Burghes
Period of Performance – May 5, 2004 to November 30, 2005
Executive Summary
Back to top |
